Eastbound Interstate 10 was closed Wednesday morning in western Arizona about four miles from the California line because of a wreck involving a tractor-trailer rig carrying fruit and produce.
The Arizona Department of Transportation says there are no nearby alternate routes and that drivers should consider delaying traffic.
A state Department of Public Safety spokesman says heavy-duty tow trucks have been dispatched to upright the truck but that there's no estimate when the freeway will reopen.
Lee says all of the trailer's load probably will have to be off-loaded.
Lee says there are no reported injuries.