The Pima County Sheriff's Department said a pedestrian was hit by a vehicle on Alvernon near I-10.
They said the man was moving when they arrived on the scene.
PCSD said the pedestrian was not in a crosswalk and was taken to the hospital in stable conditions.
The driver stayed on the scene. PCSD says impairment or speed was not a factor.
Authorities are asking drivers to avoid the area.
They said there are significant delays on both sides of the road.